Seattle Mariners (27-20) vs. Chicago White Sox (15-34)
May 21, 2025 2:10 pm EDT
The Line: Chicago White Sox 130 / Seattle Mariners -155; Over/Under: 8.5
(Get latest betting odds)
In this article, we will formulate a White Sox vs Mariners prediction for this MLB game on Wednesday, May 21, at Rate Field in Chicago, Illinois. Let’s take a look at the prediction for this MLB matchup.
Seattle Mariners Betting Preview
The Seattle Mariners (27-20, 14-9 Away) lost the series to the Blue Jays and Yankees and swept the San Diego Padres on the road. After defeating the Chicago White Sox in the opening game of this three-game series, the Mariners fell short 1-0 in Game 2. Casey Lawrence took the loss after allowing one run on six hits with two strikeouts and no walks in 5.0 innings.
This year, the Mariners average 4.80 runs per game (8th in the MLB) on a .238/.325/.400 triple-slash. When it comes to pitching, the Mariners’ staff has a 3.66 ERA (11th) and 1.30 WHIP (19th). Cal Raleigh leads the Mariners with a .241 batting average, 15 home runs, and 32 RBI this season.
The projected starting pitcher for the Mariners is Logan Evans, who is 2-1 in four starts this season, with a 2.57 ERA and 1.52 WHIP in 21.0 innings.
Chicago White Sox Betting Preview
The Chicago White Sox (15-34, 10-13 Home) snapped a five-game losing skid with a 1-0 win over the Mariners on Tuesday. Prior to this series, the White Sox were swept by the city rivals Cubs, and beat the Reds and Marlins. In last night’s 1-0 victory, Joshua Palacios drove in the only RBI, while Adrian Houser got the win after allowing no runs on two hits with two strikeouts and three walks across 6.0 innings of work.
This season, the White Sox average 3.29 runs per game (29th in the MLB) on a .216/.287/.328 triple-slash. When it comes to pitching, the White Sox’s staff has a 4.24 ERA (21st) and 1.40 WHIP (23rd). Miguel Vargas leads the White Sox with a .240 batting average, six home runs, and 21 RBI this season.
Shane Smith will take the mound for the White Sox on Wednesday. The 25-year-old right-hander has a 1-3 record in nine starts this year with a 2.05 ERA and 1.14 WHIP in 48.1 innings.
Total Runs Facts
- Each of the Mariners’ last six day games as favorites have gone OVER the total runs line.
- Each of the White Sox’s last four home games after playing the previous day have gone UNDER the total runs line.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Mariners’ last four games against American League opponents.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in six of the White Sox’s last seven games against American League opponents.
Matchup/League Facts
- The White Sox rank 29th in the league for RBIs this season (154).
- The White Sox rank 29th in the league for slugging percentage this season (.328).
- The Mariners are one of only four teams in the league to rank top 10 in both steals and home runs this season.
- The Mariners rank 5th in the league for walks this season (186).
White Sox vs Mariners Prediction
The Mariners won seven of the previous ten H2H encounters, including four of the last five. Seven of Seattle’s last ten games went Under, which was also the case in seven of Chicago’s previous ten games. I am going with another low-scoring affair here because of the starting pitchers’ matchup. Shane Smith is the White Sox’s best starter this year, and even though he’s a rookie, he has allowed more than two runs just once so far. Smith also has three shutout starts under his belt and three quality starts. Logan Evans, on the other hand, is another rookie who has impressed thus far in the season. Evans shut the Padres out in his recent start, and I am backing him to have another strong outing here. Go with Under.
