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White Sox vs Mariners Prediction 5/19/25 MLB Picks Today

Seattle Mariners (26-19) vs. Chicago White Sox (14-33)
May 19, 2025 7:40 pm EDT
The Line: Chicago White Sox 170 / Seattle Mariners -205; Over/Under: 8
(Get latest betting odds)

The Seattle Mariners and Chicago White Sox meet Monday in MLB action at Rate Field. Here’s a White Sox vs Mariners Prediction. This article will include a White Sox vs Mariners Pick.

Seattle Mariners Betting Preview

The Seattle Mariners are 26-19 on the year and play the Astros, Nationals, and Twins next. The Seattle Mariners are batting .238 on the season, have a .326 OBP, and a .402 slugging percentage. The Seattle Mariners’ pitching staff has a 3.72 ERA and a 1.32 WHIP. Julio Rodriguez leads the Seattle Mariners with 43 hits and 21 RBI, while J.P. Crawford and Cal Raleigh have combined for 81 hits and 51 RBI.

Luis Castillo gets the ball for the Seattle Mariners, and he is 3-3 with a 3.65 ERA and 39 strikeouts this season. Castillo is 1-0 with a 2.33 ERA and 23 strikeouts in his career against the Chicago White Sox.

Chicago White Sox Betting Preview

The Chicago White Sox are 14-33 on the year and play the Rangers, Mets, and Orioles next. The Chicago White Sox are batting .217 on the season, have a .288 OBP, and a .331 slugging percentage. The Chicago White Sox pitching staff has a 4.23 ERA and a 1.41 WHIP. Lenyn Sosa leads the Chicago White Sox with 41 hits and 11 RBI, while Miguel Vargas and Andrew Vaughn have combined for 71 hits and 39 RBI.

Davis Martin gets the ball for the Chicago White Sox, and he is 2-4 with a 3.65 ERA and 33 strikeouts this season. This will be Martin’s second career game against the Seattle Mariners.

Why the Chicago White Sox will win

  • The White Sox have won each of their last four games as home underdogs following a loss.
  • The Mariners have lost each of their last four games as favorites against AL Central opponents.
  • The Mariners have failed to cover the run line in each of their last seven games as favorites against AL Central opponents.
  • The underdogs have covered the run line in 11 of the Mariners’ last 12 games.
  • The Mariners have lost the first inning in three of their last four night games against AL Central opponents.
  • The White Sox have led after 5 innings in each of their last four night games.
  • The White Sox have led after 3 innings in six of their last seven home games.

Why the Seattle Mariners will win

  • The White Sox have lost each of their last seven games against teams that held a winning record.
  • The road team has won 10 of the Mariners’ last 11 games.
  • The road team has covered the run line in each of the last six games between the Mariners and White Sox.
  • The White Sox have failed to cover the run line each of their last four games against teams that held a winning record.
  • The White Sox have trailed after 3 innings in each of their last four games.
  • The Mariners have led after 5 innings in each of their last five games as road favorites against AL Central opponents.

Chicago White Sox Player Prop Facts

  • Miguel Vargas has hit at least one home run in two of the White Sox’s last three games as underdogs.
  • Miguel Vargas has recorded at least one RBI in each of the White Sox’s last four games.
  • Miguel Vargas has recorded at least one Single in six of the White Sox’s last seven games against AL West opponents.
  • Andrew Vaughn has recorded at least one hit in each of his last 11 Monday appearances with the White Sox as underdogs.
  • Andrew Benintendi has scored a run in each of his last five appearances.
  • Luis Robert ranks 1st in the league in Steals (17) this season.

Seattle Mariners Player Prop Facts

  • Jorge Polanco has hit at least one home run in three of his last four appearances at Rate Field against AL opponents that held a losing record.
  • Rowdy Tellez has recorded at least one RBI in each of the Mariners’ last six games as road favorites against AL opponents.
  • Randy Arozarena has recorded at least one Single in each of his last six road appearances against opponents that held a losing record.
  • J.P. Crawford has scored at least one run in each of his last eight appearances with the Mariners as road favorites against AL Central opponents.
  • Luis Castillo has recorded a win in four of his last five appearances against AL Central opponents that held a losing record.
  • Luis Castillo has recorded six or more strikeouts in each of his last seven Monday appearances.
  • J.P. Crawford has recorded at least one hit in each of his last 10 road appearances against AL opponents.
  • Victor Robles has recorded a Double in three of the Mariners’ last four games against AL Central opponents that held a losing record.
  • Cal Raleigh ranks T2nd in the league in Home Runs (15) this season.

White Sox vs Mariners Prediction

When the White Sox had won three games in a row, I told you guys to stay the course and keep betting against them. The White Sox have been the worst team in baseball over the last three years, and they’re dreadful for bettors already this season. Since those three wins, the White Sox have lost four straight games and have been outscored 9-33 in those games. Blindly fading the White Sox has been profitable for three years running. It also doesn’t hurt that the Mariners are coming off a nice week, and they’re throwing out an all-star pitcher in Castillo. Give me the Mariners and the RL for max betting value.

Randy Chambers's Free Pick: Seattle Mariners -1.5

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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