Dodgers vs Diamondbacks Prediction 5/21/25 MLB Picks Today

The Arizona Diamondbacks and the Los Angeles Dodgers meet Wednesday in MLB action from Dodger Stadium. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Dodgers vs Diamondbacks Prediction.

Starting Pitching Matchup

The Arizona Diamondbacks will send out Corbin Burnes for the start here, and Burnes is 3-1 with a 2.56 ERA and 43 strikeouts this season. In his last five starts against the Dodgers, Burnes is 2-2 with a 2.54 ERA and 27 strikeouts. Dustin May will get the start against the Diamondbacks here and is 1-4 with a 4.43 ERA and 41 strikeouts this season. In his last five starts against Arizona, May is 1-2 with a 2.92 ERA and 18 strikeouts.

Arizona Diamondbacks Recap

The Arizona Diamondbacks come into this game looking to bounce back from their 4-3 loss at the hands of the Dodgers in Tuesday’s matchup to fall to 26-23 on the year. After this series, the Diamondbacks will head on the road for a series against the St. Louis Cardinals.

Diamondbacks Looking To Win Rubber Match

Corbin Carroll has a team-high 57 hits with 15 home runs, 34 RBIs, 6 triples, and 9 doubles, while Josh Naylor has 53 hits with 12 doubles, 5 home runs, and 29 RBIs as well this season. Eugenio Suarez has also added 14 home runs and 38 RBIs, while Geraldo Perdomo has 37 RBIs. Naylor has also chipped in 8 stolen bases as well up to this point in the year, while Carroll has the unfortunate distinction of leading the Diamondbacks with 57 strikeouts so far this season. Carroll also has 9 stolen bases, and Perdomo has a team-high 11 stolen bases as well this season.

Why the Arizona Diamondbacks will win

Arizona Diamondbacks Player Prop Facts

Los Angeles Dodgers Recap

The Los Angeles Dodgers come into this game looking to build on their win over the Diamondbacks on Tuesday to improve to 30-19 on the year. After this series, the Dodgers will head on the road for a series against the New York Mets.

Dodgers Snap Four-Game Losing Streak

Shohei Ohtani has 59 hits, including 9 doubles, 17 home runs, 31 RBIs, and 4 triples, while Tommy Edman has 30 hits with 8 home runs and 26 RBIs. Michael Conforto has 24 hits with 9 doubles, while Teoscar Hernandez has 41 hits with 9 home runs, 10 doubles, and 34 RBIs as well this season. Ohtani has a team-high 11 stolen bases, while Max Muncy has 8 doubles but also has 47 strikeouts so far this season. Mookie Betts has also chipped in 8 home runs and 30 RBIs on the year.

Why the Los Angeles Dodgers will win

Los Angeles Dodgers Player Prop Facts

Total Runs Facts

Dodgers vs Diamondbacks Prediction

I’m on the Diamondbacks in this one. I get that it’s never really fun to go against the Dodgers, but Corbin Burnes is finally looking like the ace-level arm that the Diamondbacks were hoping they’d get when they brought him in the offseason. Burnes also has some strong numbers against the Dodgers in his career, and I think he can get the job done here. Give me the Diamondbacks in this one.

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