Blue Jays vs Padres Prediction 5/22/25 MLB Picks Today

The San Diego Padres and Toronto Blue Jays meet Thursday in MLB action at Rogers Centre. Here’s a Blue Jays vs Padres Prediction. This article will include a Blue Jays vs Padres Pick.

San Diego Padres Betting Preview

The San Diego Padres are 27-20 on the year and play the Braves, Marlins, and Pirates next. The San Diego Padres are batting .257 on the season, have a .322 OBP, and a .389 slugging percentage. The San Diego Padres pitching staff has a 3.50 ERA and a 1.18 WHIP. Manny Machado leads the San Diego Padres with 54 hits and 20 RBI, while Fernando Tatis Jr. and Luis Arraez have combined for 103 hits and 42 RBI.


Stephen Kolek gets the ball for the San Diego Padres, and he is 2-1 with a 2.33 ERA and 15 strikeouts this season. This will be Kolek’s second career game against the Toronto Blue Jays.

Toronto Blue Jays Betting Preview

The Toronto Blue Jays are 24-24 on the year and play the Rays, Rangers, and Athletics next. The Toronto Blue Jays are batting .250 on the season, have a .318 OBP, and a .384 slugging percentage. The Toronto Blue Jays’ pitching staff has a 4.13 ERA and a 1.22 WHIP. Bo Bichette leads the Toronto Blue Jays with 59 hits and 24 RBI, while Vladimir Guerrero Jr. and Alejandro Kirk have combined for 90 hits and 40 RBI.

Bowden Francis gets the ball for the Toronto Blue Jays, and he is 2-6 with a 5.63 ERA and 36 strikeouts this season. This will be Francis’s second career game against the San Diego Padres.

Why the Toronto Blue Jays will win

Why the San Diego Padres will win

Toronto Blue Jays Player Prop Facts

San Diego Padres Player Prop Facts

Blue Jays vs Padres Prediction

I’m not excited to lay juice with the Padres, as they’ve lost five straight games and have scored a combined three runs in those games. The Padres have been shut out in back-to-back games. The Padres have failed to score a run in 26 straight innings. With that said, the Padres are too talented to stay down for long. Francis also hasn’t been good this season, and that includes allowing 20 hits and 11 runs in his last 15.2 innings. In 24 home innings, Francis has a 6.75 ERA and a .299 allowed batting average. If the Padres can’t break out of their slump here, something is seriously wrong. The price is fair. Give me the Padres.

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