Twins vs Guardians Prediction 5/20/25 MLB Picks Today

The Cleveland Guardians and the Minnesota Twins meet Tuesday in MLB action from Target Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Twins vs Guardians Prediction.

Starting Pitching Matchup

The Cleveland Guardians will start Gavin Williams here, and Williams is 3-2 with a 4.29 ERA and 51 strikeouts this season. In his last five starts against the Twins, Williams is 2-2 with a 3.79 ERA and 16 strikeouts. Chris Paddack will get the start for the Twins here and is 2-3 with a 4.05 ERA and 33 strikeouts this season. In his career, Paddack is 0-0 with a 2.08 ERA and 8 strikeouts against the Guardians.

Cleveland Guardians Recap

The Cleveland Guardians come into this game looking to keep the ball rolling after Monday’s series opener was suspended with a score of 2-1, to be finished on Tuesday before this game. The Guardians still sit at 25-21 on the year as a result. After this series, the Guardians will continue on the road for another division series against the Detroit Tigers.

Guardians Drop 4^th In A Row Before Suspension

Steven Kwan leads the Guardians with 56 hits as part of a .311 batting average and 4 home runs, 9 doubles, and 17 RBIs. Kyle Manzardo has 31 hits with 4 doubles, 2 triples, 10 home runs, and a team-high 25 RBIs this year. Gabriel Arias has 8 doubles but also 43 strikeouts, and Manzardo has a team-high 44 strikeouts so far this season. Arias has also added 4 home runs and 19 RBIs, and Jose Ramirez has chipped in 9 home runs and 23 RBIs.

Why the Cleveland Guardians will win

• The Guardians have won seven of their last eight night games against AL Central opponents.
• The Twins have lost six of their last seven home games against American League opponents that held a winning record.
• The Twins have failed to cover the run line in nine of their last 10 home games against the Guardians following a loss.
• The road team has covered the run line in six of the Twins’ last seven games.

Cleveland Guardians Player Prop Facts

• Jose Ramirez has hit a home run in three of the Guardians’ last five games.
• Carlos Santana has recorded at least one RBI in four of his last five appearances after not playing the previous day.
• Steven Kwan has recorded at least one Single in each of the Guardians’ last seven road games against AL opponents that held a winning record.
• Steven Kwan has scored at least one run in seven of the Guardians’ last eight road games against AL Central opponents.
• Jose Ramirez has recorded a Double in each of the Guardians’ last five Tuesday night games at Target Field.
• Jose Ramirez has recorded at least one hit in each of the Guardians’ last 12 games.
• Steven Kwan ranks T9th in the league in Hits (56) this season.

Minnesota Twins Recap

The Minnesota Twins come into this game looking to get their record back on track after falling short in Sunday’s finale against Milwaukee before Monday’s suspension, sitting at 26-21 at the moment.

Twins Looking To Start New Win Streak

Byron Buxton has 41 hits along with 5 doubles, a team-high 10 home runs, and 27 RBIs with 8 stolen bases and 3 triples, while Carlos Correa has 35 hits with 8 doubles, and Willi Castro has 23 hits with 7 doubles as well. Harrison Bader added 4 home runs and 18 RBIs while Buxton contributed a team-high 56 strikeouts as well this season. Ty France has also added 42 hits, 8 doubles, 3 home runs, and 23 RBIs, and Trevor Larnach chipped in 42 hits with 7 home runs and 23 RBIs as well this season.

Why the Minnesota Twins will win

• The Twins have won each of their last nine games at Target Field.
• The Guardians have lost 10 of their last 11 games on the first leg of a doubleheader.
• The Twins have covered the run line in each of their last eight games against American League opponents.
• The Guardians have failed to cover the run line in nine of their last 10 road games against teams that held a winning record.

Minnesota Twins Player Prop Facts

• Bailey Ober has recorded a win in each of his last four home appearances against AL Central opponents.
• Trevor Larnach has recorded at least one hit in each of his last 11 appearances after not playing the previous day.
• Bailey Ober has recorded five or more strikeouts in eight of his last nine home appearances against AL opponents.
• Ryan Jeffers has hit a home run in three of his last five appearances in night games against AL teams that held a winning record.
• Ty France has recorded at least one RBI in five of his last six home appearances against AL opponents that held a winning record.
• Ty France has recorded at least one Single in seven of the Twins’ last eight games against AL Central opponents that held a winning record.
• Trevor Larnach has scored at least one run in each of his last nine appearances after not playing the previous day.

Total Runs Facts

• Nine of the Twins’ last 10 home games on the first leg of a doubleheader have gone UNDER the total runs line.
• Six of the Guardians’ last seven games have gone UNDER the total runs line.

Twins vs Guardians Prediction

I’m on the Twins here. I just think that the Twins are the better team in better form right now, and I’m not much of a Gavin Williams fan to begin with. It’ll be interesting to see how Monday’s game being suspended affects things, but I think that the Twins can keep it going and keep a new win streak going here. Not sure this one would hit 13 games as well, but I think Minnesota gets the W here. Give me Minnesota.