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Marlins vs Cubs Prediction 5/20/25 MLB Picks Today

Chicago Cubs (28-20) vs. Miami Marlins (19-27)
May 20, 2025 6:40 pm EDT
The Line: Miami Marlins 130 / Chicago Cubs -155; Over/Under: 8.5
(Get latest betting odds)

In this article, we will formulate a Marlins vs Cubs prediction for this MLB game on Tuesday, May 20th at loanDepot park in Miami, Florida. Let’s take a look at the prediction for this MLB matchup. 

Miami Marlins Betting Preview

The Miami Marlins are 19-27 this season after they won game one in this series by a score of 8-7 on Monday. Miami blew a 6-3 lead in the middle innings, but they scored two runs in the bottom of the ninth to escape with the win. The Marlins recorded 11 hits in the game, and they were led by Sanchez, who went 3-5 with one home run and four RBIs in the win. Miami started Cabrera, who allowed five hits and three earned runs over 5.0 innings, while Bellozo picked up the win in relief. 


Prior to this series, the Marlins won two out of three against the Rays, but lost two out of three against the Cubs before that. Miami has won four of its last five games, and they are currently last in the NL East standings. The Miami pitching staff has a 5.37 ERA with a 1.47 WHIP and a .262 opponent batting average, while the offense has scored 195 runs with a .249 batting average and a .313 on-base percentage this season. Kyle Stowers has led Miami with 10 home runs and 30 RBIs, while Matt Mervis has added seven home runs and 14 RBIs this year. The projected starting pitcher for Miami is Ryan Weathers, who is 1-0 with a 1.80 ERA and a 0.60 WHIP over 5.0 innings pitched this season. 

Chicago Cubs Betting Preview

The Chicago Cubs are 28-20 this year after they lost the first game in this series on Monday night. Chicago trailed 6-3 in the fifth inning, but they took a 7-6 lead in the sixth, before blowing the lead in the ninth for the loss. The Cubs recorded 12 hits in the game, and they were led by Amaya, who went 2-3 with one home run and five RBIs in the loss. Chicago started Brown, who allowed seven hits and six earned runs over 4.2 innings, while Palencia blew the save and picked up the loss. 

Prior to this series, the Cubs swept the White Sox in three games and won two out of three against the Marlins. Chicago has won five of their last seven games, and they are currently first in the NL Central standings. The Chicago pitching staff has a 4.02 ERA with a 1.29 WHIP and a .250 opponent batting average, while their offense has scored 277 runs with a .256 batting average and a .332 on-base percentage this season. Pete Crow-Armstrong has led Chicago with 12 home runs and 38 RBIs, while Seiya Suzuki has added 11 home runs and 39 RBIs this year. The projected starting pitcher for Chicago is Jameson Taillon, who is 2-3 with a 4.53 ERA and a 1.11 WHIP over 49.2 innings pitched this year. 

Why the Cubs will beat the Marlins

  • The Cubs have won each of their last 12 games following a road loss.
  • The Marlins have lost 15 of their last 18 night games against National League opponents following a win.
  • The Cubs have covered the run line in eight of their last nine games following a road loss.
  • The Marlins have failed to cover the run line in six of their last seven night games against the Cubs following a home win.
  • The Marlins have trailed after 5 innings in eight of their last nine Tuesday games against NL Central opponents that held a winning record.
  • The Cubs have led after 3 innings in three of their last four games.

Total Runs Facts

  • Five of the Cubs’ last six road games against NL East opponents have gone OVER the total runs line.
  • Six of the Marlins’ last eight games after playing the previous day have gone UNDER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Cubs’ last four games.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Marlins’ last four night games at LoanDepot Park.

Miami Marlins Player Prop Facts

  • Jesus Sanchez has hit a home run in each of the Marlins’ last two home games against the Cubs.
  • Jesus Sanchez has recorded at least one RBI in each of the Marlins’ last three home games against NL opponents.
  • Otto Lopez has scored a run in seven of his last eight Tuesday appearances.
  • Otto Lopez has recorded at least one Single in each of his last four appearances in night games against NL teams that held a winning record.
  • Otto Lopez has recorded at least one hit in 12 of his last 13 home appearances against opponents that held a winning record.

Chicago Cubs Player Prop Facts

  • Seiya Suzuki has hit a home run in three of the Cubs’ last five night games against NL East opponents that held a losing record.
  • Justin Turner has recorded a Double in each of his last three appearances with his team as a road favorite against the Marlins.
  • Jameson Taillon has recorded a win in four of his last five appearances against NL East opponents that held a losing record.
  • Carson Kelly has recorded at least one Single in each of his last six appearances with his team as a road favorite against NL opponents.
  • Ian Happ has scored at least one run in seven of his last eight appearances in night games against teams that held a losing record.
  • Ian Happ has recorded an RBI in each of his last four appearances with the Cubs as road favorites against NL East opponents.
  • Dansby Swanson has recorded at least one hit in each of the Cubs’ last 14 road games against NL opponents that held a losing record.

Marlins vs Cubs Prediction 

Miami was able to complete a very nice comeback for the win in game one of this series, and they have won four of their last five games. The Marlins are 13-13 at home this year, while the Cubs are 13-10 on the road. Chicago has won three of their last four games, and they have the highest scoring offense in the MLB currently. The Cubs are starting Taillon, who has allowed eight earned runs and 13 hits over his last 10.0 innings. The Marlins are starting Weathers, who allowed two hits and one earned run against Chicago last week in his first outing of the year. Miami may have some momentum coming into this game, but we are getting one of the best offensive teams in the MLB at a decent price here. Take the Cubs. 

David Racey's Free Pick: Cubs ML

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David Racey

David started writing about sports in 2015, but sports has been his passion for as long as he can remember. David spends most of his free time watching pretty much anything sports related from Baseball to Tennis and everything in between. David likes to analyze statistics and recent results to form an unbiased opinion on whatever game he is breaking down. Follow David on Twitter at @itsyerboi41

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