Pirates vs Reds Prediction 5/19/25 MLB Picks Today

In this article, we will formulate a Pirates vs Reds prediction for this MLB game on Monday, May 19th at PNC Park in Pittsburgh, Pennsylvania. Let’s take a look at the prediction for this MLB matchup. 

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates are 15-32 this year after they lost all three games against the Phillies by scores of 4-8, 2-5, and 0-1. In their game three loss, Pittsburgh got a great pitching performance from Skenes, but couldn’t find any runs in the shutout loss. The Pirates recorded six hits in the game, and they were led by McCutchen, Reynolds, Horwitz, Canario, Kiner-Falefa, and Davis, who all had one hit in the game. Pittsburgh started Skenes, who allowed three hits and one earned run over 8.0 innings, while striking out nine. 


Prior to that series, the Pirates lost two out of three against the Mets, but did win two out of three against the Braves before that. Pittsburgh has lost five of its last six games, and they are currently last in the NL Central standings. The Pittsburgh pitching staff has a 4.08 ERA with a 1.27 WHIP and a .240 opponent batting average, while their offense has scored 141 runs with a .217 batting average and a .297 on-base percentage this season. Bryan Reynolds has led Pittsburgh with six home runs and 22 RBIs, while Andrew McCutchen has added three home runs and 14 RBIs this year. The projected starting pitcher for Pittsburgh is Mitch Keller, who is 1-5 with a 4.15 ERA and a 1.33 WHIP over 52.0 innings pitched this year. 

Cincinnati Reds Betting Preview

The Cincinnati Reds are 24-24 this season after they swept Cleveland in three games by scores of 5-4, 4-1, and 3-1. In their game three win, Cincinnati scored the first three runs in the game, and they were able to hang on for the win. The Reds recorded nine hits in the game, and they were led by Benson, who went 3-4 with two home runs and three RBIs in the win. Cincinnati started Abbott, who allowed four hits and zero earned runs over 5.0 innings for the win, while Pagan picked up the save. 

Prior to that series, the Reds lost two out of three against the White Sox and two out of three against the Astros. Cincinnati has won four games in a row, and they are currently third in the NL Central standings. The Cincinnati pitching staff has a 3.58 ERA with a 1.17 WHIP and a .223 opponent batting average, while their offense has scored 220 runs with a .243 batting average and a .320 on-base percentage this season. Elly De La Cruz has led Cincinnati with eight home runs and 31 RBIs, while Austin Hays has added six home runs and 17 RBIs this year. The projected starting pitcher for Cincinnati is Nick Lodolo, who is 3-4 with a 3.42 ERA and a 1.08 WHIP over 52.2 innings pitched this season. 

Why the Reds will beat the Pirates

Total Runs Facts

Pittsburgh Pirates Player Prop Facts

Cincinnati Reds Player Prop Facts

Matchup/League Facts

Pirates vs Reds Prediction 

Pittsburgh comes into this series after a very disappointing loss on Sunday afternoon, and they are the lowest-scoring team in the MLB this year. The Pirates are 9-13 at home this season, while the Reds are 11-12 on the road. Cincinnati finally has some momentum, and they are starting Lodolo, who has allowed three earned runs or more in three of his last five starts. Pittsburgh is going with Keller, who has allowed two earned runs or fewer in three of his last five starts. I backed the Pirates on Sunday afternoon, but can’t do the same here after watching them at the plate. Take the Reds to win. 

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