Guardians vs Phillies Prediction 5/10/25 MLB Picks Today

The Philadelphia Phillies and the Cleveland Guardians meet Saturday in MLB action from Progressive Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Guardians vs Phillies Prediction.

Starting Pitching Matchup

The Philadelphia Phillies will start Ranger Suarez here and Suarez is 0-0 with a 17.18 ERA and 6 strikeouts this season. This will be Suarez’s second career start against the Guardians. Tanner Bibee will start for the Guardians here and is 3-2 with a 4.26 ERA and 28 strikeouts this season. This will be Bibee’s second career start against the Phillies.

Philadelphia Phillies Recap

The Philadelphia Phillies come into this game looking to rebound after a 6-0 loss to the Guardians on Friday to fall to 22-16 on the year. After this series, the Phillies will head home for a set against the St. Louis Cardinals.

Phillies Have Three-Game Win Streak Snapped

Nick Castellanos has 39 hits with 10 doubles including 4 home runs and 21 RBIs while Kyle Schwarber has 35 hits with a team-high 12 home runs and 28 RBIs as well on the year. Bryce Harper has 6 stolen bases, 6 home runs and 20 RBIs. Trea Turner also has 44 hits with a team-high 9 stolen bases. Max Kepler has 7 doubles and Bryson Stott has 5 doubles, 2 triples, 3 homers and 20 RBIs while Stott also has 7 stolen bases as well this season.

Why the Philadelphia Phillies will win

Philadelphia Phillies Player Prop Facts

Cleveland Guardians Recap

The Cleveland Guardians come into this game looking to build on their win from the series opener on Friday. After this series, the Guardians will square off against the Milwaukee Brewers.

Guardians Win Three In A Row

Steven Kwan leads the Guardians with 49 hits as part of a .333 batting average and 4 home runs, 7 doubles and 17 RBIs. Kyle Manzardo has 23 hits with 3 doubles, a triple, 8 home runs and a team-high 21 RBIs as well this year. Gabriel Arias has a team-high 7 doubles but also 33 strikeouts and Manzardo has a team-high 33 strikeouts so far this season. Arias has also added 4 home runs and 16 RBIs and Jose Ramirez has chipped in 5 home runs and 17 RBIs.

Why the Cleveland Guardians will win

Cleveland Guardians Player Prop Facts

Total Runs Facts

Guardians vs Phillies Prediction

I’m on the Phillies here. I get the case to be made for the Guardians, who are playing well right now. But the thing is that I don’t think that Ranger Suarez was as bad as his season debut would’ve indicated if you looked at that box score. He still has solid strikeout stuff, and the Guardians have been one of the less effective teams against left-handed pitching as of late.

Bibee hasn’t been as sharp as you’d expect from a staff ace, as he’s expected to be for Cleveland this season. The Guardians have still been doing a solid job against right-handed pitching as of late, despite a goose egg on Friday. I’ll roll with Philadelphia for the bounce back win here.

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