Nationals vs Cardinals Prediction 5/10/25 MLB Picks Today

The St. Louis Cardinals and Washington Nationals meet Saturday in MLB action at Nationals Park. Here’s a Nationals vs Cardinals Prediction. This article will include a Nationals vs Cardinals Pick.

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 20-19 on the year and play the Phillies, Royals, and Tigers next. The St. Louis Cardinals are batting .262 on the season, have a .337 OBP, and a .402 slugging percentage. The St. Louis Cardinals pitching staff has a 3.97 ERA and a 1.25 WHIP. Brendan Donovan leads the St. Louis Cardinals with 47 hits and 19 RBI, while Willson Contreras and Nolan Arenado have combined for 72 hits and 36 RBI.


Andre Pallante gets the ball for the St. Louis Cardinals, and he is 2-2 with a 4.75 ERA and 21 strikeouts this season. Pallante is 1-1 with a 7.36 ERA and 9 strikeouts in his career against the Washington Nationals.

Washington Nationals Betting Preview

The Washington Nationals are 17-22 on the year and play the Braves, Orioles, and Braves next. The Washington Nationals are batting .241 on the season, have a .311 OBP, and a .382 slugging percentage. The Washington Nationals pitching staff has a 5.47 ERA and a 1.46 WHIP. James Wood leads the Washington Nationals with 42 hits and 23 RBI, while Keibert Ruiz and Nathaniel Lowe have combined for 73 hits and 42 RBI.

Trevor Williams gets the ball for the Washington Nationals, and he is 2-3 with a 5.86 ERA and 30 strikeouts this season. Williams is 5-6 with a 4.93 ERA and 82 strikeouts in his career against the St. Louis Cardinals.

Why the Washington Nationals will win

Why the St. Louis Cardinals will win

Washington Nationals Player Prop Facts

St. Louis Cardinals Player Prop Facts

Nationals vs Cardinals Prediction

The Cardinals are rolling with six straight wins and a pitching staff that’s produced back-to-back shutouts and allowed a combined one run in their last three games. The Nationals pitching staff has bee getting rocked during this losing stretch, and Williams has played a role in those struggles. Through 35.1 innings, Williams has a 5.86 ERA and .317 allowed batting average. It’s not much better at home in 15.1 innings, as Williams has a 5.28 ERA and .271 allowed batting average.

Pallante has had his issues on the season, especially on the road, where he has a 5.66 ERA and .289 allowed batting average in 20.2 innings. However, the Cardinals are arguably the hottest team in baseball this week. I’ll trust that and lay the cheap price with the road team.

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