Marlins vs Cubs Prediction 5/21/25 MLB Picks Today

The Chicago Cubs and Miami Marlins meet Wednesday in MLB action at loanDepot park. Here’s a Marlins vs Cubs Prediction. This article will include a Marlins vs Cubs Pick.

Chicago Cubs Betting Preview

The Chicago Cubs are 29-20 on the year and play the Reds, Rockies, and Reds next. The Chicago Cubs are batting .261 on the season, have a .336 OBP, and a .448 slugging percentage. The Chicago Cubs pitching staff has a 3.96 ERA and a 1.28 WHIP. Pete Crow-Armstrong leads the Chicago Cubs with 22 hits and 39 RBI, while Nico Hoerner and Kyle Tucker have combined for 103 hits and 56 RBI.

Cade Horton gets the ball for the Chicago Cubs, and he is 2-0 with a 6.00 ERA and 7 strikeouts this season. This will be Horton’s first career game against the Miami Marlins.

Miami Marlins Betting Preview

The Miami Marlins are 19-28 on the year and play the Angels, Padres, and Giants next. The Miami Marlins are batting .248 on the season, have a .312 OBP, and a .390 slugging percentage. The Miami Marlins’ pitching staff has a 5.56 ERA and a 1.49 WHIP. Kyle Stowers leads the Miami Marlins with 49 hits and 30 RBI, while Xavier Edwards and Eric Wagaman have combined for 83 hits and 23 RBI.

Max Meyer gets the ball for the Miami Marlins, and he is 3-4 with a 4.47 ERA and 59 strikeouts this season. This will be Meyer’s second career game against the Chicago Cubs.

Why the Miami Marlins will win

Why the Chicago Cubs will win

Miami Marlins Player Prop Facts

Chicago Cubs Player Prop Facts

Marlins vs Cubs Prediction

The Cubs are the better team playing the better baseball, but I’m looking at the over in this spot. Both offenses have had success in this series, and that should continue with the quick turnaround. Horton has allowed 11 hits and six runs in nine innings this season. Meyer has allowed 21 hits and 13 earned runs in his last 16.1 innings, and he’s allowed 18 earned runs in his last 20.1 innings. The Marlins have had a lot of double-digit scoring games over the last couple of weeks, and this could be another with the way both pitchers look. Give me the over on Wednesday afternoon.

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