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Orioles vs Twins Prediction 5/15/25 MLB Picks Today

Minnesota Twins (23-20) vs. Baltimore Orioles (15-26)
May 15, 2025 12:35 pm EDT
The Line: Baltimore Orioles -142 / Minnesota Twins 120; Over/Under: 9
(Get latest betting odds)

In this article, we will formulate an Orioles vs Twins prediction for this MLB game on Thursday, May 15, at Oriole Park at Camden Yards in Baltimore, Maryland. Let’s take a look at the prediction for this MLB matchup.

Minnesota Twins Betting Preview

The Minnesota Twins (23-20, 8-14 Away) are currently the hottest team in the entire MLB after recording ten consecutive wins. Following a four-game losing skid, the Twins beat the Red Sox, swept the Orioles and Giants, and won the opening two games of the series against the Baltimore Orioles on the road. In the latest 8-6 victory, Kody Clemens led the offense with four RBI, while Simeon Woods Richardson pitched for 4.0 innings in a no-decision, allowing six runs on eight hits with four strikeouts and two walks. Kody Funderburk was credited with the win.

This season, the Twins average 4.00 runs per game (21st in the MLB) on a .238/.306/.373 triple-slash. When it comes to pitching, the Twins’ staff has a 3.32 ERA (5th) and 1.16 WHIP (4th). Byron Buxton leads the Twins with a .258 batting average, nine home runs, and 26 RBI this season.

Chris Paddack will take the mound for the Twins on Thursday. The 29-year-old right-hander has a 1-3 record in eight starts this year with a 4.76 ERA and 1.29 WHIP in 39.2 innings.

Baltimore Orioles Betting Preview

The Baltimore Orioles (15-26, 8-11 Home) lost the series to the Royals and Twins, beat the Angels, and lost the opening two games of the current series against the Minnesota Twins at home. Baltimore had a 6-5 lead until the 8th inning when the Twins scored three runs and secured an 8-6 win. Cedric Mullins blasted a grand slam in the 3rd to lead his team, while Chayce McDermott pitched for 3.0 innings in a no-decision, allowing four runs on four hits with five strikeouts and three walks. Yennier Cano took the loss.

This year, the Orioles average 3.77 runs per game (25th in the MLB) on a .227/.296/.386 triple-slash. When it comes to pitching, the Orioles’ staff has a 5.31 ERA (27th) and 1.48 WHIP (27th). Cedric Mullins leads the Orioles with a .230 batting average, eight home runs, and 25 RBI this season.

The projected starting pitcher for the Orioles is Tomoyuki Sugano, who is 4-2 in eight starts this season, with a 2.72 ERA and 1.01 WHIP in 46.1 innings.

Why the Orioles will beat the Twins

  • The Twins have lost each of their last 12 Thursday day games as road underdogs against American League opponents.
  • The Orioles have led after 3 innings in each of their last four day games against AL Central opponents.
  • The Twins have trailed after 5 innings in four of their last five day games.

Total Runs Facts

  • Nine of the Twins’ last 11 games after playing the previous day have gone UNDER the total runs line.
  • Twelve of the Orioles’ last 15 day games as favorites have gone OVER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in five of the Orioles’ last six games as favorites against AL Central opponents.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in 14 of the Twins’ last 17 day games against American League opponents.

Matchup/League Facts

  • The Orioles rank 29th in the league for opponent batting average this season (.277).
  • The Orioles rank 28th in the league for hits this season (304).
  • The Twins are one of only five teams in the league to rank top 10 in both strikeouts and walks allowed this season.
  • The Twins rank 6th in the league for ERA this season (3.38).

Orioles vs Twins Prediction

The teams have traded wins in the past couple of years, each recording five in the previous ten H2H encounters. The Twins did win five in a row, and are the hottest teams in baseball at the moment, but I am backing the Orioles to snap that positive streak because they will start Sugano. Tomoyuki is by far the best Orioles starter this season, and he hasn’t allowed more than three runs in a game yet. Sugano surrendered only three runs in total in his last three starts. Although Chris Paddack is pitching very well recently and his ERA continues to drop, I am giving a slight advantage to the hosts.

Oliver Zivic's Free Pick: Orioles ML

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Oliver Zivic

Professional journalist and expert bettor with 20+ years of experience. I cover Football (soccer), NFL, NBA, NHL, MLB, CFB, and CBB.

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