Reds vs Guardians Prediction 5/18/25 MLB Picks Today

The Cleveland Guardians and Cincinnati Reds meet Sunday in MLB action at Great American Ball Park. Here’s a Reds vs Guardians Prediction. This article will include a Reds vs Guardians Pick.

Cleveland Guardians Betting Preview

The Cleveland Guardians are 25-20 on the year and play the Twins, Tigers, and Dodgers next. The Cleveland Guardians are batting .232 on the season, have a .306 OBP, and a .381 slugging percentage. The Cleveland Guardians’ pitching staff has a 4.16 ERA and a 1.41 WHIP. Steven Kwan leads the Cleveland Guardians with 56 hits and 17 RBI, while Jose Ramirez and Gabriel Arias have combined for 83 hits and 42 RBI.

Luis Ortiz gets the ball for the Cleveland Guardians, and he is 2-4 with a 4.78 ERA and 49 strikeouts this season. Ortiz is 1-0 with a 1.69 ERA and 22 strikeouts in his career against the Cincinnati Reds.

Cincinnati Reds Betting Preview

The Cincinnati Reds are 23-24 on the year and play the Pirates, Cubs, and Royals next. The Cincinnati Reds are batting .242 on the season, have a .320 OBP, and a .393 slugging percentage. The Cincinnati Reds pitching staff has a 3.64 ERA and a 1.16 WHIP. Elly De La Cruz leads the Cincinnati Reds with 46 hits and 31 RBI, while TJ Friedl and Gavin Lux have combined for 87 hits and 36 RBI.

Andrew Abbott gets the ball for the Cincinnati Reds, and he is 2-0 with a 2.10 ERA and 38 strikeouts this season. Abbott is 1-1 with a 6.14 ERA and 6 strikeouts in his career against the Cleveland Guardians.

Why the Cincinnati Reds will win

• The home team has won each of the last five games between the Guardians and Reds.
• The Guardians have lost each of their last eight games as underdogs against the Reds following a loss.
• The Reds have covered the run line in seven of their last eight home games against American League opponents that held a winning record.
• The Guardians have failed to cover the run line in four of their last five games at Great American Ball Park.
• The Reds have won the first inning in each of their last three games as favorites against the Guardians.
• The Reds have led after 3 innings in four of their last five games against opponents that held a winning record.
• The Reds have led after 5 innings in four of their last five games against opponents that held a winning record.

Why the Cleveland Guardians will win

• The Reds have lost each of their last nine games as home favorites against AL Central opponents following a win.
• The underdogs have won four of the Guardians’ last five games.
• The Reds have failed to cover the run line in each of their last 11 games as home favorites against AL Central opponents following a win.
• The Guardians have covered the run line in seven of their last eight games as underdogs against NL Central opponents.
• The Guardians have led after 3 innings in each of their last four day games against the Reds.
• The Guardians have led after 5 innings in each of their last five day games against the Reds at Great American Ball Park.

Cincinnati Reds Player Prop Facts

• Spencer Steer has recorded a Double in three of the Reds’ last four games as favorites.
• Will Benson has hit a home run in each of the Reds’ last three games against AL Central opponents.
• Elly De La Cruz has scored at least one run in each of the Reds’ last six games as favorites.
• Santiago Espinal has recorded at least one Single in each of his last six appearances in day games against AL Central teams that held a winning record.
• Spencer Steer has recorded at least one hit in each of the Reds’ last 10 home games.
• Jeimer Candelario has recorded at least one RBI in each of his last four appearances against the Guardians.
• Elly De La Cruz ranks 4th in the league in Steals (15) this season.

Cleveland Guardians Player Prop Facts

• Jose Ramirez has hit a home run in three of the Guardians’ last four games against opponents that held a losing record.
• Jose Ramirez has recorded at least one RBI in five of the Guardians’ last six day games against NL teams that held a losing record.
• Jose Ramirez has recorded at least one Single in each of his last eight appearances with the Guardians as underdogs.
• Jose Ramirez has scored at least one run in six of the Guardians’ last seven games against opponents that held a losing record.
• Steven Kwan has recorded at least one hit in each of his last 14 Sunday appearances with the Guardians as underdogs.
• Steven Kwan ranks T4th in the league in Hits (56) this season.

Reds vs Guardians Prediction

The Guardians are having a rough week, and it’s hard seeing things turn around with Ortiz on the hill. Ortiz has a 4.78 ERA and 1.36 WHIP on the season, and he has a 7.29 ERA and .287 allowed batting average in 21 road innings. The Reds are finally starting to string wins together, and Abbott has been strong this season with his 2.10 ERA and 1.07 WHIP. In his last 15 innings, Abbott has allowed 11 hits and one earned run. In 15 home innings, Abbott has a 1.20 ERA and a .170 allowed batting average. This feels like two teams heading in different directions, and the Reds have the clear starting pitching edge. Give me the Reds and the cheap price.