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Phillies vs Pirates Prediction 5/16/25 MLB Picks Today

Pittsburgh Pirates (15-29) vs. Philadelphia Phillies (25-18)
May 16, 2025 6:45 pm EDT
The Line: Philadelphia Phillies -230 / Pittsburgh Pirates 190; Over/Under: 8.5
(Get latest betting odds)

The Pittsburgh Pirates and Philadelphia Phillies meet Friday in MLB action at Citizens Bank Park. Here’s a Phillies vs Pirates Prediction. This article will include a Phillies vs Pirates Pick.

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates are 15-29 on the year and play the Reds, Brewers, and Diamondbacks next. The Pittsburgh Pirates are batting .220 on the season, have a .301 OBP, and a .328 slugging percentage. The Pittsburgh Pirates’ pitching staff has a 4.01 ERA and a 1.26 WHIP. Ke’Bryan Hayes leads the Pittsburgh Pirates with 40 hits and 15 RBI, while Bryan Reynolds and Isiah Kiner-Falefa have combined for 66 hits and 28 RBI.


Andrew Heaney gets the ball for the Pittsburgh Pirates, and he is 2-3 with a 3.15 ERA and 36 strikeouts this season. Heaney is 0-2 with an 8.64 ERA and 6 strikeouts in his career against the Philadelphia Phillies.

Philadelphia Phillies Betting Preview

The Philadelphia Phillies are 25-18 on the year and play the Rockies, Athletics, and Braves next. The Philadelphia Phillies are batting .257 on the season, have a .335 OBP, and a .402 slugging percentage. The Philadelphia Phillies’ pitching staff has a 3.90 ERA and a 1.26 WHIP. Trea Turner leads the Philadelphia Phillies with 50 hits and 14 RBI, while Nick Castellanos and Kyle Schwarber have combined for 88 hits and 56 RBI.

Ranger Suarez gets the ball for the Philadelphia Phillies, and he is 1-0 with a 5.91 ERA and 11 strikeouts this season. Suarez is 3-0 with a 1.80 ERA and 31 strikeouts in his career against the Pittsburgh Pirates.

Why the Philadelphia Phillies will win

  • The Phillies have won each of their last 11 home games following a home loss.
  • The Pirates have lost each of their last six road games against NL East opponents following a win.
  • The Pirates have failed to cover the run line in each of their last five games as road underdogs against National League opponents following a road win.
  • The Phillies have covered the run line in four of their last five night games against National League opponents following a home loss.

Why the Pittsburgh Pirates will win

  • The Phillies have lost three of their last four games as favorites against National League opponents.
  • The underdogs have won three of the last four games between the Pirates and Phillies.
  • The Pirates have covered the run line in each of their last six games as road underdogs against NL East opponents.
  • The Phillies have failed to cover the run line in each of their last four home games.

Philadelphia Phillies Player Prop Facts

  • Kyle Schwarber has hit a home run in four of the Phillies’ last seven night games against opponents that held a losing record.
  • J.T. Realmuto has recorded at least one RBI in each of his last four appearances against NL Central opponents at Citizens Bank Park.
  • Ranger Suarez has recorded six strikeouts in three of his last four appearances at Citizens Bank Park.
  • Trea Turner has recorded at least one Single in each of his last six appearances in night games against NL Central teams that held a losing record.
  • Trea Turner has scored at least one run in each of the Phillies’ last six games at Citizens Bank Park against opponents that held a losing record.
  • Alec Bohm has recorded at least one hit in each of his last 13 appearances at Citizens Bank Park against opponents that held a losing record.
  • Max Kepler has recorded a Double in four of his last five home appearances against the Pirates.
  • Kyle Schwarber ranks 7th amongst qualified players for Slugging Percentage (.580) this season.

Pittsburgh Pirates Player Prop Facts

  • Andrew McCutchen has recorded a Double in three of his last four appearances after not playing the previous day.
  • Jared Triolo has scored a run in each of the Pirates’ last four games at Citizens Bank Park against opponents that held a winning record.
  • Oneil Cruz has hit a home run in two of his last three road appearances against NL East opponents that held a winning record.
  • Ke’Bryan Hayes has recorded at least one hit in each of his last nine appearances in night games against NL teams that held a winning record.
  • Ke’Bryan Hayes has recorded at least one Single in each of his last nine appearances in night games against NL teams that held a winning record.
  • Jack Suwinski has recorded at least one RBI in three of the Pirates’ last four games at Citizens Bank Park against opponents that held a winning record.

Phillies vs Pirates Prediction

The Pirates can’t string together wins and haven’t won two straight games since April 22-23. Heaney has also been shaky lately, allowing 17 hits and 10 runs in his last 14.1 innings. The Phillies are not only the better team playing the more consistent ball, but Suarez is coming off seven shutout innings against the Guardians. Suarez has also had success against the Pirates, which includes holding current hitters to a .200 batting average and four strikeouts in 20 at-bats. I need to see the Pirates win games in a row before they get my attention. Until then, the Pirates are fade material. Give me the Phillies and the RL for max betting value.

Randy Chambers's Free Pick: Philadelphia Phillies -1.5

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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